From Molecule to Drug Target for Asthma

eBook - 1999
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This important volume describes the latest advances in all areas of interleukin-5 (IL5) research, pooling the insights of over 65 biological researchers, pharmaceutical scientists, and clinicians, representing institutions as diverse as the Mayo Clinic, the National Lung and Heart Institute, the John Curtin School of Medical Research, the Geneva Biomedical Research Institute, the Flanders' Interuniversity Institute for Biotechnology, and the University of Tokyo.
Details IL5-related antiallergy drugs currently in development at Glaxo Wellcome and Schering-Plough Research Institute
Reviewing approaches toward small molecule antagonists and inhibitors, Interleukin-5
highlights the structure and function of IL5 and IL5 receptors
explores the interaction between IL5 and eotaxin
analyzes agents that down-regulate IL5 production
evaluates studies on IL5 knockout and transgenic mice
outlines the regulation of IL5 gene expression
discusses the protein structure of IL5
covers the signalling pathways used by the IL5 receptor
relates the structure and role of receptor subunits in signal transduction
and more
Featuring over 1250 references, tables, drawings, photographs, and micrographs, Interleukin-5 is suitable for pulmonologists and pulmonary disease specialists; immunologists; clinical allergists; internists; chest, intensive care, primary care, and family practice physicians; respiratory therapists; physiologists; pathologists; cell and molecular biologists; and medical school students in these disciplines.
Publisher: New York, N.Y. : M. Dekker, [1999], ©1999
ISBN: 9780585352220
Branch Call Number: 616.079 In
Description: 1 online resource (xviii, 381 pages) : illustrations
Alternative Title: Interleukin five


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